Alessandra M. Norris

This study shows that blocking intramuscular adipose tissue (IMAT) formation after muscle injury improves muscle regeneration and function in mice.

This study identifies DHH as a key ligand in the Hedgehog signaling pathway that regulates fibro/adipogenic progenitor fate during skeletal muscle regeneration, preventing adipogenesis and promoting fibrosis.

The paper applies Cellpose and a new ImageJ plugin to automatically and accurately segment myofibers in murine skeletal muscle, enabling unbiased quantification across different staining and fixation conditions.