Sébastien Bastide

This study uses TATTOO-seq to identify spatial and cell type-specific regulatory programs during limb development and shows how perturbations affect cell fate and spatial organization.

The paper uses in vivo CRISPR editing to analyze Fgf8 regulatory elements in the AER and MHB, revealing distinct patterns of enhancer redundancy and function.

The paper investigates catch-up growth in fetal mice after inducing cell cycle arrest in chondrocytes, revealing local and systemic compensatory mechanisms that maintain body proportions.