Andreas Hörnblad

The paper identifies gene regulatory networks linked to GABA signaling in glioblastoma using multi-omics data and machine learning, showing GABA signaling promotes tumor growth through non-synaptic mechanisms.

This study shows that ATX-304, an AMPK activator, reduces oxidative stress and improves MASLD in mice by altering liver metabolism and lipid distribution.

This study maps the promoter-enhancer interactome and regulatory landscape in glioblastoma, revealing rewiring of chromatin interactions and gene expression changes related to synaptic communication.

The paper uses in vivo CRISPR editing to analyze Fgf8 regulatory elements in the AER and MHB, revealing distinct patterns of enhancer redundancy and function.