Author

Jonah Simon

Brown UniversityORCID 0000-0001-9386-6839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Stewart Campbell· 1 shared Aenne HarbertsiD· 1 shared Anne C. HartiD· 1 shared Bernd SchnabliD· 1 shared Burak UnsaliD· 1 shared Christopher J. OalmanniD· 1 shared Debanjan DhariD· 1 shared Jennifer T. Lau· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Stewart Campbell

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2 papers

Recent·Most cited

Pharmacology & ToxicologyMolecular MetabolismPeer-reviewedAug 18, 2026

Targeting Microbial Bile Salt Hydrolase Reprograms Bile Acid Metabolism and Ameliorates Metabolic Dysfunction-Associated Steatohepatitis in Mice

Wenchao Wei, Radka Graf, Yanhan Wang…·Bernd Schnabl

This study shows that the BSH inhibitor GR-7 reduces steatosis, inflammation, and fibrosis in a mouse model of MASH through bile acid metabolism reprogramming and immune modulation.

DOI 10.1016/j.molmet.2026.102430

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 11, 2019

Disrupted Autophagy and Neuronal Dysfunction in C. elegans Knockin Models of FUS Amyotrophic Lateral Sclerosis

Saba Baskoylu, Natalie Chapkis, Burak Unsal…·Anne C. Hart

This study uses C. elegans knock-in models to show that autophagy dysfunction contributes to neuronal defects in FUS-related ALS, independent of SQSTM1/p62 function.

2 citations

C. elegansexperimental assay

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