Bernd Schnabl

Bacteriophage susceptibility in clinical Enterococcus faecalis reflects host genomic background and Epa-associated phage adsorption

The paper investigates phage susceptibility in E. faecalis clinical isolates, linking it to host genomic background and Epa-associated phage adsorption patterns.

Targeting Microbial Bile Salt Hydrolase Reprograms Bile Acid Metabolism and Ameliorates Metabolic Dysfunction-Associated Steatohepatitis in Mice

This study shows that the BSH inhibitor GR-7 reduces steatosis, inflammation, and fibrosis in a mouse model of MASH through bile acid metabolism reprogramming and immune modulation.

IL-17RC signaling connects intestinal microbiota and neuroimmune interactions in atherosclerosis

This study shows IL-17RC signaling in the intestine prevents atherosclerosis by controlling microbiota and perivascular innervation, with loss of IL-17RC increasing inflammation and disease.

Systematic analysis of transcriptional and epigenetic effects of genetic variation in Kupffer cells enables discrimination of cell intrinsic and environment-dependent mechanisms

The paper analyzes how genetic variation affects gene expression and epigenetics in Kupffer cells, distinguishing between cell intrinsic and environment-dependent mechanisms.