Author

Khondakar Sayef Ahammed

The Ohio State UniversityORCID 0000-0001-9403-0937Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ambro van HoofiD· 3 shared Anita H. CorbettiD· 1 shared Bhawana IsraniiD· 1 shared Danielle A. GarsiniD· 1 shared Davide MeiiD· 1 shared Eun Young HuhiD· 1 shared Hannah B. WilsoniD· 1 shared Huiqing HuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Ambro van HoofORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 20, 2026

Characterization of tRNA ligase function in pathogenic fungi and trypanosomes reveals the ligase domain as a promising drug target

Khondakar Sayef Ahammed, Pedro Miramón, Lukas Schrettenbrunner…·Ambro van Hoof

The paper identifies the Trl1 sealing domain as a promising drug target for antifungal and anti-trypanosomal therapies by analyzing its essentiality in pathogenic fungi and trypanosomes.

DOI 10.64898/2026.08.16.745097

humanmouse

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Genetic & Genomic MedicinemedRxivPreprintAug 2, 2026

Biallelic protein truncating EXOSC6 variants cause a neurodevelopmental disorder with cerebellar atrophy, ataxia, and global developmental delay

Khondakar Sayef Ahammed, Renzo Guerrini, Milo B. Fasken…·Davide Mei

The paper reports a patient with a neurodevelopmental disorder caused by biallelic EXOSC6 variants, expanding the known spectrum of exosomopathies.

DOI 10.64898/2026.07.30.26359120

humanwhole-exome sequencing

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GeneticsRNAPeer-reviewedFeb 2, 2024

Fungi of the order Mucorales express a 'sealing-only' tRNA ligase

Khondakar Sayef Ahammed, Ambro van Hoof

The paper identifies that Mucorales fungi use a sealing-only tRNA ligase, implying that targeting sealing activity could lead to broader-spectrum antifungals.

8 citations

fungi (other)experimental assay

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