Brian Patrick Head

This study shows that Catestatin improves heart metabolic flexibility by enhancing mitochondrial structure and function through binding to ATP synthase.

This study shows APP induces reactive astrogliosis in vitro and in vivo by remodeling intermediate filaments, enhancing cytokine production, and activating the IFN pathway.

This paper identifies GLT8D1 mutations as a cause of ALS by disrupting neurotrophin signaling in lipid rafts through reduced ganglioside expression.

This study shows that re-expressing caveolin-1 in Alzheimer's disease mice improves cognitive function and reduces neurodegeneration without affecting amyloid deposits.