Suborno Jati

This study shows that Catestatin improves heart metabolic flexibility by enhancing mitochondrial structure and function through binding to ATP synthase.

This study shows that beta-hydroxybutyrate (betaHB) improves neuronal Tau proteostasis and reduces Tau aggregation in tauopathy models, independent of its ketolysis for ATP production.

This study shows that Catestatin reduces Tau pathology and amyloid plaque formation by inhibiting adrenergic signaling in mouse models of neurodegenerative diseases.

This study investigates the roles of CgA and its derived peptides, CST and PST, in pancreatic islet function and glucose homeostasis using knockout mice, revealing their opposing effects on insulin resistance and metabolic processes.

This study shows that CST suppresses melanoma progression and drug resistance by modulating multiple signaling pathways.

This study shows that CgA deficiency reduces tau pathology and improves cognitive function in tauopathy models by modulating epinephrine-alpha-adrenergic receptor signaling.