Author

Jacob J. Parker

Yale UniversityORCID 0000-0001-9425-6418Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:Bayesian inference· 1 Approach:deep learning· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Clemens R. ScherzeriD· 3 shared Geidy E. SerranoiD· 3 shared Idil TuncaliiD· 3 shared Joshua Z. LeviniD· 3 shared Nathan HaywoodiD· 3 shared Sean SimmonsiD· 3 shared Thomas G. BeachiD· 3 shared Xianjun DongiD· 3 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Clemens R. ScherzerORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 29, 2026

Single cell eQTL mapping reveals convergent glial-neuronal risk architecture in Parkinson's disease

Zechuan Lin, Jacob Parker, Vanitha Nithianandam…·Clemens R. Scherzer

The paper fine-maps PD GWAS signals across cell types, revealing convergent glial-neuronal risk genes and a shared vesiculopathy network.

DOI 10.64898/2026.04.24.720642

𝕏 PostBluesky

GenomicsGenome biologyPeer-reviewedApr 11, 2026

Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data

Sean Simmons, Xian Adiconis, Nathan Haywood…·Joshua Z. Levin

This paper develops computational tools for allelic imbalance analysis using single-nucleus RNA-seq and demonstrates their application in a Parkinson's disease cohort.

1 citation

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 23, 2026

Integrating Long-Read Structural Variant Analysis with single-nucleus RNA-seq to Elucidate Gene Expression Effects in Disease

Kwanho Kim, Zechuan Lin, Sean Simmons…·Joshua Z. Levin

This study integrates long-read WGS and single-nucleus RNA-seq to identify structural variants affecting gene expression in Parkinson's disease with cell type resolution.

DOI 10.64898/2026.03.20.713192

humanlong-read sequencing

𝕏 PostBluesky