Alistair N. Hume

This paper develops the first cell-active covalent inhibitors of RAB27-effector interactions, showing enantioselectivity and improved potency over a previously reported toxic compound.

The paper identifies an ancient polymorphism in myosin I a/b that determines left-right asymmetry in Japanese snails without causing pathology.

This study shows that alternating current can enhance drug delivery and overcome resistance in brain tumors by modulating intracellular trafficking.