Maria Sopena-Rios

The impact of sex, age, and genetic ancestry on DNA methylation across tissues

The paper quantifies how sex, age, genetic ancestry, and BMI influence DNA methylation across 9 tissues in 424 individuals, finding that ancestry and age have the greatest impact.

Single-cell atlas of transcript usage remodelling in antiviral immune responses across human populations

The paper creates a single-cell atlas of transcript usage changes during antiviral immune responses in humans, showing lineage-specific and ancestry-related variations across influenza and SARS-CoV-2 infections.

Multimodal data analysis reveals asynchronous aging dynamics across female reproductive organs

The paper integrates histological and RNA-seq data to show asynchronous aging dynamics across female reproductive organs, with menopause marking a key transition in the uterus and vagina.

Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence

This study uses single-cell RNA sequencing to analyze immune aging in 982 donors, revealing sex-specific changes in immune cell composition and function during aging.

In vivo single-cell profiling of lncRNAs during Ebola virus infection

This study profiles lncRNA expression in single cells during Ebola virus infection in vivo, revealing cell-type specific changes and potential roles in immune response and viral hijacking.