Ferrán Reverter

Single-cell atlas of transcript usage remodelling in antiviral immune responses across human populations

The paper creates a single-cell atlas of transcript usage changes during antiviral immune responses in humans, showing lineage-specific and ancestry-related variations across influenza and SARS-CoV-2 infections.

Exploring functional conservation in silico: a new machine learning approach to RNA-editing

The paper introduces a machine learning approach to assess RNA-editing functional conservation using random forest and biLSTM networks, predicting editing events and analyzing conservation across species.

A fast non-parametric test of association for multiple traits

The paper introduces a fast non-parametric test for genetic associations with multiple traits, demonstrating its effectiveness in splicing QTL mapping and hippocampal subfield GWAS.

In vivo single-cell profiling of lncRNAs during Ebola virus infection

This study profiles lncRNA expression in single cells during Ebola virus infection in vivo, revealing cell-type specific changes and potential roles in immune response and viral hijacking.

Identification and analysis of splicing quantitative trait loci across multiple tissues in the human genome

The paper identifies and analyzes splicing quantitative trait loci (sQTLs) across multiple tissues using the GTEx dataset, revealing their role in splicing regulation and disease.

A vast resource of allelic expression data spanning human tissues

The paper presents a large ASE resource from GTEx v8 with 431 million SNP-level and 153 million haplotype-level measurements, and extends phASER to estimate cis regulatory variant effect sizes.

Determinants of telomere length across human tissues

The paper examines telomere length variation across 6,391 tissue samples from 952 individuals, showing tissue-specific differences, positive correlations between tissues, and associations with age and ancestry.

A Quantitative Proteome Map of the Human Body

The paper quantifies protein levels across 32 human tissues and compares them to transcriptome data, revealing insights into post-transcriptional regulation and disease mechanisms.

A limited set of transcriptional programs define major cell types

The paper identifies five major cell types based on transcriptional programs in human tissues and shows their composition correlates with tissue morphology and disease.

Atlas of transcriptionally active transposable elements in human adult tissues

The paper maps transcriptionally active transposable elements in human adult tissues, identifying thousands of tissue-specific and phenotype-associated TEs.

Modified penetrance of coding variants by cis-regulatory variation shapes human traits

The paper shows that cis-regulatory variation modifies the penetrance of coding variants, affecting disease risk in cancer and autism, and demonstrates this through experimental validation.