Lisa E. Hensley

This study identifies eltrombopag olamine and quercetin as CCHFV entry inhibitors using a BSL-2 pseudotype screening platform validated against authentic CCHFV under BSL-4 conditions.

This paper designs an mRNA-LNP vaccine by integrating RNA, lipid, and antigen engineering to achieve 90% protection in a murine model.

This study shows that growth hormone excess in mice causes liver aging by increasing glycation stress, which can be reversed with glycation-lowering compounds.

This study uses Massively Parallel Ribosome Profiling to identify thousands of viral ORFs, including non-canonical ones, and shows their impact on HLA-I peptides and protein synthesis regulation.

This study investigates the pathogenicity and transmissibility of a bovine-derived HPAI H5N1 B3.13 virus in pigs, finding susceptibility but limited replication and no transmission.

This study investigates H5N1 clade 2.3.4.4b virus infection in calves and lactating cows, finding that mammary gland infection causes severe mastitis and reduced milk production, with transmission likely via milk rather than respiratory routes.

This study profiles lncRNA expression in single cells during Ebola virus infection in vivo, revealing cell-type specific changes and potential roles in immune response and viral hijacking.

This paper develops CRISPR-Cas13a-based diagnostics for real-time detection of Ebola and Lassa viruses in field settings, demonstrating sensitivity and usability in clinical samples.

The paper introduces CATCH, a method for designing compact and scalable probe sets to enhance metagenomic sequencing sensitivity, demonstrating improved viral genome recovery and diversity preservation.