Ahilya N. Sawh

The paper introduces a whole-embryo spatial transcriptomics method and generates a comprehensive gene expression and chromatin accessibility atlas in zebrafish embryos.

The paper develops CeSCALE to analyze lineage-resolved conformation-transcription relationships in C. elegans embryos, revealing robust inheritance of local chromatin features during development.

The paper identifies three types of megabase-scale heterochromatin domains in C. elegans using single-molecule tracing and shows their developmental dynamics and structural differences.

The paper shows that AMPK regulates small RNA pathways in somatic cells to control germline stem cell quiescence during energy stress in C. elegans.

The paper uses multiplex DNA fluorescence in situ hybridization to study maternal and paternal chromosome organization in C. elegans, finding that paternal chromosomes adopt maternal folding patterns in embryos.