Author

Vijay Kumar Bhardwaj

The University of Texas Health Science Center at HoustonORCID 0000-0001-9511-6206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alemayehu Abebe GorfeiD· 2 shared Alison Gomeiz· 1 shared Chris B. Marshall· 1 shared Frank McCormickiD· 1 shared Gamze BildikiD· 1 shared Hailing Yang· 1 shared John F. HancockiD· 1 shared Junchen LiuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alemayehu Abebe GorfeORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 22, 2026

DIRAS3 broadly suppresses signaling from diverse oncogenic KRAS hotspot variants through an inhibitory interface

Gamze Bildik, Hailing Yang, Weiqun Mao…·Zhen Lu

This study identifies DIRAS3 as a tumor suppressor that inhibits diverse oncogenic KRAS variants through a specific inhibitory interface, with a mimetic showing broad suppression of KRAS-driven signaling.

DOI 10.64898/2026.10.21.760748

humanproteomics

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BiophysicsbioRxivPreprintSep 18, 2025

GPR174 Antagonism: Structure, Function, and Dynamics

Vijay Kumar Bhardwaj, Alemayehu Abebe Gorfe

This study models GPR174 bound to an antagonist and compares its dynamics to LysoPS, revealing distinct ligand-specific mechanisms and potential for immunotherapeutic antagonists.

DOI 10.1101/2025.09.18.677133

structural biologybiophysical modeling

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