Junchen Liu

This study shows that galectin-3's carbohydrate recognition domain maintains plasma membrane phosphatidylserine, which is necessary for KRAS function.

This study identifies DIRAS3 as a tumor suppressor that inhibits diverse oncogenic KRAS variants through a specific inhibitory interface, with a mimetic showing broad suppression of KRAS-driven signaling.

This study shows that lipid acyl chain remodeling via LPCAT3 affects KRAS nanoclustering and oncogenic activity by altering membrane composition.

This paper shows eIF2B activates mutant KRAS by forming a complex with SOS at the plasma membrane and regulating glycosphingolipid biosynthesis.

This study shows glycosphingolipids regulate phosphatidylserine transport at ER-PM contact sites by maintaining ORP5 and ORP8 localization and function.