Baoying Huang

The paper determines the structure of the poxvirus portal complex and its pore, revealing their role in molecular transport and antiviral target potential.

This study identifies adaptive mutations in PRRSV nsp12 that enable evasion of host proteasomal and autophagic degradation, enhancing viral replication and infectivity.

The paper identifies CASP3-GSDME-mediated trophoblast pyroptosis as a driver of systemic inflammation in early-onset preeclampsia and shows Vitamin D suppresses this process.

This study uses cryo-ET and STA to reveal the architecture of mature MPXV particles and identifies irregular virions with distorted core walls.