Nagarjuna Reddy Pamudurti

This study shows circRNAs are highly stable in the aging fly brain and can indicate age and environmental experience.

This study shows that SARS-CoV-2 Nsp14 alters the host transcriptome, splicing, and circRNA levels, with IMPDH2 mediating these effects through GTP regulation.

This paper describes a method to specifically knock down circRNAs in vivo and shows that circRNA downregulation affects fly development and transcriptome.

This paper develops a shRNA-based strategy to knock down circMbl in Drosophila, revealing its functional roles in development, behavior, and synaptic function.