Author

Michela Zaffagni

Brandeis UniversityORCID 0000-0002-2483-8727Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Sebastián KadeneriD· 2 shared Inés Lucía PatopiD· 1 shared Jenna M HarrisiD· 1 shared Jonathan D. ZiriniD· 1 shared Nagarjuna Reddy PamudurtiiD· 1 shared Norbert PerrimoniD· 1 shared Raghuvir ViswanathaiD· 1 shared Sinead NguyeniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Sebastián KadenerORCID

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2 papers

Recent·Most cited

SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

Michela Zaffagni, Jenna M Harris, Inés Lucía Patop, Nagarjuna Reddy Pamudurti, Sinead Nguyen, Sebastián Kadener

This study shows that SARS-CoV-2 Nsp14 alters the host transcriptome, splicing, and circRNA levels, with IMPDH2 mediating these effects through GTP regulation.

eLife · Mar 11, 2022Peer-reviewedMolecular Biology

CRISPR-Cas13 mediated Knock Down in Drosophila cultured cells.

Raghuvir Viswanatha, Michela Zaffagni, Jonathan D. Zirin, Norbert Perrimon, Sebastián Kadener

This study develops and optimizes CRISPR-Cas13 tools for RNA knockdown in Drosophila cells, improving efficiency and reducing toxicity.

bioRxiv · Nov 1, 2020 · PreprintMolecular Biology