Author

Tobias Opialla

Max Delbrück CenterORCID 0000-0001-9527-8061Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:C. elegans· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alexander BlumeiD· 1 shared Amin Shadfar· 1 shared Anna Reid· 1 shared Anne‐Lise RoyeriD· 1 shared Baris TursuniD· 1 shared Bruno Le BizeciD· 1 shared Carole MignéiD· 1 shared Dieter BeuleiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alexander BlumeORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 23, 2026

Depletion of the isocitrate dehydrogenase 3 subunit IDHA-1 licenses germ cell-to-neuron direct reprogramming in C. elegans

Nida Fatima, Anna Reid, Amin Shadfar…·Baris Tursun

This study identifies IDHA-1 as a barrier to direct reprogramming of germ cells to neurons in C. elegans, showing metabolic and epigenetic mechanisms that maintain germ cell identity.

DOI 10.64898/2026.09.22.753437

C. elegansexperimental assay

𝕏 PostBluesky

BioinformaticsMetabolitesPeer-reviewedAug 21, 2019

WiPP: Workflow for improved Peak Picking for Gas Chromatography-Mass Spectrometry (GC-MS) data

Nico Borgsmüller, Yoann Gloaguen, Tobias Opialla…·Jennifer Kirwan

WiPP improves GC-MS peak detection by combining multi-algorithm results with machine learning-based quality assessment, enhancing accuracy and enabling algorithm comparison.

30 citations

metabolomicsmachine learning (classical)

𝕏 PostBluesky