Sergio Domínguez-López

This study examines how long-term methamphetamine self-administration affects glutathione levels, mitochondrial respiration, and dopamine neuron activity in mice.

This study finds that male mice show age-related decline in substantia nigra dopamine neuron firing, while females remain resilient, with increased expression of Parkinson's-related genes in males.

This study shows that deleting the neurotensin receptor 1 in mice reduces methamphetamine self-administration and prevents the decrease in dopamine neuron firing frequency associated with prolonged use.