Holly Van Remmen

This study corrects a pathogenic ATAD3A variant in iPSCs using CRISPR-Cas9-induced gene conversion without donor templates, showing high efficiency and dependence on HR proteins.

This study shows that 12/15-LOX is essential for inflammation resolution and skeletal muscle regeneration by regulating lipid mediators and myogenic progenitor cell function.

This study identifies TIMM17A as a key mediator of HSF1-driven mitochondrial biogenesis and function in cancer cells, revealing a mechanism linking HSF1 to mitochondrial protein import and energy production.

This study investigates mitochondrial dysfunction and its link to fatigue in Sjögren's disease by analyzing T cell metabolism and mitophagy transcriptional signatures.

This study examines how long-term methamphetamine self-administration affects glutathione levels, mitochondrial respiration, and dopamine neuron activity in mice.