Shwetha V. Kumar

The paper identifies ASX-173 as a potent ASNS inhibitor that enhances the anti-cancer effects of L-asparaginase in leukemia and shows its potential across multiple cancer types.

PCA-Plus enhances principal component analysis to better detect, visualize, and quantify batch effects and group differences in multi-omic data.

The paper compiles protein response data from cancer cell lines to drug perturbations, showing improved drug sensitivity prediction and building a protein-drug connectivity map with an accessible data portal.