Author

Lin Tan

The University of Texas MD Anderson Cancer CenterORCID 0000-0001-8440-5643Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lin Tan2 papers · The University of Texas MD Anderson Cancer Center

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Bao Quoc TraniD· 2 shared Iqbal MahmudiD· 2 shared John N. WeinsteiniD· 2 shared Philip L. LorenziiD· 2 shared Sara A. MartineziD· 2 shared Alena I. DorofeevaiD· 1 shared Alvina I. KhamidullinaiD· 1 shared Alyx E. Gray· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Bao Quoc TranORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aberrant oxidative metabolism selects for TET2-deficient hematopoietic stem and progenitor cells

Katia E. Niño, Vera Ademà, Alyx E. Gray, Courtney M Cowan, Wolfgang E. Schleicher, Mohsen Hosseini, Sierra N. Bennett, Sweta B. Patel, Steven Moreira, Etienne P. Danis, Feyiang Ma, Hsin-Ying Lin, Tracy N. Young, Colin A. Anderson, Devyani Sharma, , Eric Martin Pietras

This study shows that aberrant oxidative metabolism drives the selection of TET2-deficient hematopoietic stem and progenitor cells in clonal hematopoiesis, with the pentose phosphate pathway playing a compensatory role.

bioRxiv · Mar 2, 2026 · PreprintCancer Biology

The ASNS inhibitor ASX-173 potentiates L-asparaginase anticancer activity

Victor Vyacheslavovich Tatarskiy, Wai-Kin Chan, Lin Tan, Alvina I. Khamidullina, Iqbal Mahmud, Shwetha V. Kumar, Julia Nuzhina, Sara A. Martinez, Bao Quoc Tran, Anna Skwarska, Nataliya G Pavlenko, Alena I. Dorofeeva, Marina Konopleva, Dmitry V. Genis, John N. Weinstein, , Philip L. Lorenzi

The paper identifies ASX-173 as a potent ASNS inhibitor that enhances the anti-cancer effects of L-asparaginase in leukemia and shows its potential across multiple cancer types.

bioRxiv · Jul 3, 2025 · PreprintCancer Biology

Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity

Yun Xiong, Lin Tan, Waikin Chan, Eric S. Yin, Sri Ramya Donepudi, Jibin Ding, Bo Wei, Bao Quoc Tran, Sara A. Martinez, Iqbal Mahmud, Hamish I. Stewart, Daniel J. Hermanson, John N. Weinstein, Philip L. Lorenzi

The paper introduces UFP-MS, a fast proteomics method, and applies it to study drug effects on mouse tissues, revealing tissue-specific metabolic changes.

bioRxiv · Sep 25, 2024 · PreprintSystems Biology