Author

Jair L. Siqueira-Neto

University of California San DiegoORCID 0000-0001-9574-8174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Arne AlderiD· 1 shared Charisse Flerida A. PasajeiD· 1 shared Christian ScheureriD· 1 shared Dale TayloriD· 1 shared David A. FidockiD· 1 shared Dina CoertzeniD· 1 shared Elizabeth A. WinzeleriD· 1 shared Francisco‐Javier GamoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

Arne AlderORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

MicrobiologyACS Chemical BiologyPeer-reviewedJun 13, 2026

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity Against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of PfArk1 and Hemozoin Formation

Kathryn J. Wicht, John G. Woodland, Larnelle F. Garnie…·Kelly Chibale

This study shows that CHIR-124, a human Chk1 inhibitor, is active against Plasmodium falciparum through dual inhibition of PfArk1 and hemozoin formation, suggesting polypharmacology as a strategy for antimalarial drugs.

5 citationstop 1%

humanmouse

𝕏 PostBluesky