Author

Nikita Rifel

Max Planck Institute of BiochemistryORCID 0000-0001-9581-6931Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adarsh MohananiD· 1 shared Aleksandar LaliciD· 1 shared Antoine VallotiD· 1 shared Imre GáspáriD· 1 shared Johanna GassleriD· 1 shared Kiku-e K. TachibanaiD· 1 shared Laura Cuenca Rico· 1 shared Laura Gómez HernándeziD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Adarsh MohananORCID

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1 paper

Recent·Most cited

Zygotic genome activation by the totipotency pioneer factor Nr5a2

Johanna Gassler, Wataru Kobayashi, Imre Gáspár, Siwat Ruangroengkulrith, Adarsh Mohanan, Laura Gómez Hernández, Pavel Kravchenko, Maximilian Kümmecke, Aleksandar Lalic, Nikita Rifel, Robert John Ashburn, Maciej Zaczek, Antoine Vallot, Laura Cuenca Rico, Sabrina Ladstätter, Kiku-e K. Tachibana

This study identifies Nr5a2 as a key activator of zygotic genome activation in mouse embryos, showing it regulates 72% of ZGA genes and is essential for development beyond the 2-cell stage.

Science · Nov 24, 2022Peer-reviewedDevelopmental Biology