Author

Johanna Gassler

Institute of Molecular BiotechnologyORCID 0000-0002-4408-6577Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:Hi-C· 1

Frequent Co-Authors

Kiku-e K. TachibanaiD· 2 shared Sabrina LadstätteriD· 2 shared Adarsh MohananiD· 1 shared Aleksandar LaliciD· 1 shared Antoine VallotiD· 1 shared Hugo B. BrandãoiD· 1 shared Ilya M. FlyameriD· 1 shared Imre GáspáriD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

Kiku-e K. TachibanaORCID

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2 papers

Recent·Most cited

Developmental BiologySciencePeer-reviewedNov 24, 2022

Zygotic genome activation by the totipotency pioneer factor Nr5a2

Johanna Gassler, Wataru Kobayashi, Imre Gáspár…·Kiku-e K. Tachibana

This study identifies Nr5a2 as a key activator of zygotic genome activation in mouse embryos, showing it regulates 72% of ZGA genes and is essential for development beyond the 2-cell stage.

158 citationstop 1%

mouseChIP-seq

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GenomicsThe EMBO JournalPeer-reviewedDec 7, 2017

A Mechanism of Cohesin-Dependent Loop Extrusion Organizes Zygotic Genome Architecture

Johanna Gassler, Hugo B. Brandão, Maxim Imakaev…·Kiku-e K. Tachibana

The paper shows cohesin-dependent loop extrusion organizes zygotic chromatin into loops and domains, with distinct effects on maternal and paternal genomes.

381 citationstop 1%

mouseHi-C

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