Author

Anika Reifschneider

Ludwig-Maximilians-Universität MünchenORCID 0000-0001-9598-9373Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anja CapelliD· 3 shared Christian HaassiD· 3 shared Gilbert Di PaoloiD· 3 shared Arthur LiesziD· 2 shared Bettina van Lengerich· 2 shared Brigitte NuscheriD· 2 shared Claudia Krenner· 2 shared Dominik PaquetiD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Anja CapellORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedJan 24, 2026

TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism

Astrid Feiten, Kilian Dahm, Kai Schlepckow…·Christian Haass

This study investigates how TREM2 expression levels affect microglial function, metabolism, and response to TREM2 agonists in a mouse model of Alzheimer's disease.

39 citationstop 1%

mousebulk RNA-seq

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NeurosciencebioRxivPreprintJan 16, 2024

Enhanced legumain activity links progranulin deficiency to TDP-43 pathology in frontotemporal lobar degeneration

Sophie Robinson, Marvin Reich, Maria‐Teresa Mühlhofer…·Anja Capell

This study shows that reduced progranulin leads to increased legumain activity, which promotes TDP-43 pathology in FTLD, suggesting legumain as a therapeutic target.

5 citations

mousehuman

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NeurosciencebioRxivPreprintJul 8, 2021

Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology

Anika Reifschneider, Sophie Robinson, Bettina van Lengerich…·Christian Haass

This study shows that TREM2 deficiency reduces microglial hyperactivation in GRN-deficient models but does not rescue lysosomal dysfunction or neurodegeneration biomarkers.

2 citations

mouseexperimental assay

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