Sarah Joseph

This study identifies a new form of nonsuppressible viremia in HIV patients on ART, linked to macrophage tropism and genetic diversity, distinct from previously known CD4+ T cell-related NSV.

This study investigates how HIV-1 Nef's ability to downregulate MHC-I affects the size of the replication-competent viral reservoir in South African women on ART, finding a significant association between MHC-I downregulation and reservoir size.

The paper identifies that HIV-1 rebound virus primarily originates from a small number of lineages that entered the reservoir near ART initiation, despite the reservoir containing older sequences.

The paper measures CSF proteins in HIV-1 infected and uninfected individuals, identifying patterns of protein changes associated with CNS injury and treatment effects.