Michael J. Smallegan

The paper curates an accessible human surfaceome using an LLM pipeline, outperforming existing databases and identifying new candidate surface proteins.

This study investigates the temporal dynamics of lncRNA Firre-mediated epigenetic and transcriptional regulation, showing rapid and persistent effects on gene expression.

This study uses machine learning to improve PCR success rates, achieving 81% prediction accuracy and identifying 15 under-optimized features.

The paper re-analyzes ENCODE data to identify reservoir promoters and human-specific SVA-repeat regulation using reproducible methods.

The paper identifies lncMYH7b as a regulatory long noncoding RNA in the human heart that influences the ratio of β-MyHC to α-MyHC through TEAD1/TEAD3 regulation, independent of miR-499.