Author

Fredrik Wermeling

Karolinska University HospitalORCID 0000-0001-9633-677XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexander EspinosaiD· 2 shared Lars KlareskogiD· 2 shared Aaron R. WinkleriD· 1 shared Alejandro Fernandez-WoodbridgeiD· 1 shared Anatoly P. DubnovitskyiD· 1 shared Bence RéthiiD· 1 shared Birce Akpinar· 1 shared Bruno RaposoiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Alexander EspinosaORCID

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 30, 2026

A new humanized TCR transgenic mouse model to study citrullinated tenascin C reactive T cells relevant to rheumatoid arthritis

Marlene Schülein, M. Gomes Afonso, Merel Sijbranda…·Bruno Raposo

DOI 10.64898/2026.02.12.705563

mouseflow cytometry

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 4, 2026

Correlate: A Web Application for Analyzing Gene Sets and Exploring Gene Dependencies Using CRISPR Screen Data

Soham Deolankar, Fredrik Wermeling

Correlate is a web tool that analyzes CRISPR screen data to find gene relationships and support hypothesis generation and experimental design.

DOI 10.64898/2026.04.02.716070

humanCRISPR screen

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Cancer BiologybioRxivPreprintNov 21, 2025

A neoantigen-microbead platform for personalized T cell cancer vaccination

Long Jiang, Birce Akpinar, Yue Li…·Hans Grönlund

This study develops a neoantigen-microbead platform for personalized T cell cancer vaccination and shows it effectively inhibits tumor growth in a mouse model.

DOI 10.1101/2025.11.21.689667

mouseproteomics

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ImmunologybioRxivPreprintFeb 16, 2024

Dnmt3a mutations limit normal and autoreactive Tfh differentiation

Yunbing Shen, Zhaojun Li, Sanjaykumar V. Boddul…·Fredrik Wermeling

This study shows that Dnmt3a mutations impair Tfh differentiation, contributing to autoimmune joint inflammation and reduced immune responses.

DOI 10.1101/2024.02.16.580463

mousegenetic perturbation / CRISPR

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