Author

Tony Warne

MRC Laboratory of Molecular BiologyORCID 0000-0001-9646-6080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher G. TateiD· 2 shared Andrew G. W. LeslieiD· 1 shared Ankur Gupta· 1 shared Artù BreueriD· 1 shared Arun K. ShuklaiD· 1 shared Asger Tønnesen· 1 shared Christopher G. ShuttleiD· 1 shared Dimitrios G. StamouiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Christopher G. TateORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 28, 2024

Multimodal intrinsic activation of GPCRs in ultrastable plasma membrane nanodomains

Gabriele Kockelkoren, Jens Carstensen, Line Lauritsen…·Dimitrios G. Stamou

This paper quantifies GPCR intrinsic activation at the plasma membrane, revealing spatial multimodality with most receptors showing negligible spontaneous activation.

DOI 10.1101/2024.02.28.582451

humanfluorescence / live-cell microscopy

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Molecular BiologyNaturePeer-reviewedJun 17, 2020

Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor

Yang Lee, Tony Warne, Rony Nehmé…·Christopher G. Tate

This paper determines the cryo-EM structure of the β1AR-βarr1 complex bound to formoterol and compares it to the β1AR-Gs complex, revealing structural differences that inform biased agonism.

297 citationstop 1%

experimental assay

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