Author

Andrew G. W. Leslie

MRC Laboratory of Molecular BiologyORCID 0000-0002-5229-3656Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Approach:experimental assay· 1

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Arun K. ShuklaiD· 1 shared Christopher G. TateiD· 1 shared Hemlata Dwivedi‐AgnihotriiD· 1 shared Javier García‐NafríaiD· 1 shared Madhu ChaturvediiD· 1 shared Patricia C. EdwardsiD· 1 shared Rony Nehmé· 1 shared Shubhi PandeyiD· 1 shared

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Arun K. ShuklaORCID

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Molecular BiologyNaturePeer-reviewedJun 17, 2020

Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor

Yang Lee, Tony Warne, Rony Nehmé…·Christopher G. Tate

This paper determines the cryo-EM structure of the β1AR-βarr1 complex bound to formoterol and compares it to the β1AR-Gs complex, revealing structural differences that inform biased agonism.

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experimental assay

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