Author

Yu Chen

Duke UniversityORCID 0000-0001-9651-9875Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yu Chen14 papers · Bristol-Myers Squibb (United States)

Biology Disciplines

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Immunology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Daniel R. SabaniD· 2 shared Joan KalnitskyiD· 2 shared Sejiro LittletoniD· 2 shared Victor L. PereziD· 2 shared Agnes Acevedo Canabal· 1 shared Allison M. Nguyen-ThaiiD· 1 shared Anna MatyniaiD· 1 shared Areej Ammar· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Daniel R. SabanORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 24, 2026

Neutrophil remodeling is associated with human meibomian gland dysfunction and enables IFN-γ- and PAD4-dependent gland obstruction in mice

Cole J. Beatty, Symon Ma, Oleg Kolupaev…·Daniel R. Saban

This study identifies a remodeled neutrophil state associated with meibomian gland dysfunction, showing IFN-γ and PAD4-dependent obstruction in mice.

DOI 10.64898/2026.08.19.744915

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 28, 2025

The Cornea Harbors a Tricellular Neuro-Immune Niche that Underpins Touch Sensation

Sejiro Littleton, EM Jacob, Yu Chen…·Daniel R. Saban

The paper identifies a tricellular niche in the cornea involving macrophages, nerves, and Schwann cells that supports Piezo2-mediated touch sensation.

3 citations

𝕏 PostBluesky

BioinformaticsAgingPeer-reviewedAug 24, 2021

A systematic dissection of human primary osteoblasts in vivo at single-cell resolution

Yun Gong, Junxiao Yang, Xiao‐Hua Li…·Hong‐Wen Deng

This study identifies three human osteoblast subtypes using scRNA-seq, revealing a novel subtype with unique gene expression and functional roles in bone and hematopoiesis.

37 citations

𝕏 PostBluesky