BioengineeringNaturePeer-reviewed
Transferrin Receptor Targeting Chimeras (TransTACs) for Membrane Protein Degradation
Dingpeng Zhang, Jhoely Duque-Jimenez, Francesco Facchinetti…·Xin X. Zhou
This paper introduces TransTACs, a method for degrading membrane proteins by redirecting them to lysosomal degradation using the transferrin receptor, showing high efficiency across various protein types.
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