Author

William W. Feng

Dana-Farber Cancer InstituteORCID 0000-0002-8976-5020Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Alexander Wang YingiD· 2 shared Cigall KadochiD· 2 shared Adrian Gerold SacheriD· 1 shared Ajinkya PatiliD· 1 shared Akshay Sankar· 1 shared Bengul GokbayrakiD· 1 shared Caitlyn Weston· 1 shared Claudia Gentile· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Alexander Wang YingORCID

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2 papers

Recent·Most cited

mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion

Claudia Gentile, William W. Feng, Sean M. Lenahan, Alexander Wang Ying, Daren C. Card, Florence T.H. Wu, Nhu‐An Pham, Nikolina Radulovich, Pinjiang Mary Cao, K. Hueniken, Quan Li, Ming‐Sound Tsao, JOSEPH S. KULESZA, Madeline M. Hinkley, Lishu Liao, , Cigall Kadoch

This study shows that inhibiting mSWI/SNF complexes enhances the effectiveness of KRAS inhibitors in lung cancers by reversing epithelial-mesenchymal transition resistance.

bioRxiv · Mar 1, 2026 · PreprintCancer Biology

Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas

Jessica D. St. Laurent, Grace Dydian Xu, Alexander Wang Ying, Bengul Gokbayrak, Ajinkya Patil, João A. Paulo, Kasey S. Cervantes, Shary Yuting Chen, William W. Feng, Akshay Sankar, Daniel D. Samé Guerra, Jun Qi, Dana S. Neel, Jason L. Hornick, David L. Kolin, , Cigall Kadoch

This study identifies shifted mSWI/SNF subcomplex stoichiometry in DDEC/UEC cancers and shows that SMARCA4/2 inhibitors reduce tumor growth and synergize with chemotherapy.

Nature Genetics · Oct 20, 2025Peer-reviewedMolecular Biology