Author

Kyle S. Osborne

University of UtahORCID 0000-0001-9654-7040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:machine learning (classical)· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandra RicheyiD· 2 shared Hosiana AbeweiD· 2 shared Jason GertziD· 2 shared Noel KitcheniD· 2 shared Alex J. BottiD· 1 shared Brian K. DalleyiD· 1 shared Craig M. RushiD· 1 shared Erin M. WissinkiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenomics

Alexandra RicheyORCID

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2 papers

Recent·Most cited

Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer

Alexandra Richey, Noel Kitchen, Craig M. Rush, Jeffery M. Vahrenkamp, Hosiana Abewe, Kyle S. Osborne, Alex J. Bott, Brian K. Dalley, Jared P. Rutter, Jason Gertz

The paper identifies genomic features affecting ERα binding and gene expression in endometrial cancer, finding cell-type-specific transcription factors and distinct predictive features compared to breast cancer.

Genome Research · Sep 1, 2026Peer-reviewedGenomics

Cis-regulatory control of transcriptional timing and noise in response to estrogen

Matthew Ginley-Hidinger, Hosiana Abewe, Kyle S. Osborne, A. Richey, Noel Kitchen, Katelyn L. Mortenson, Erin M. Wissink, John T. Lis, Xiaoyang Zhang, Jason Gertz

This study identifies cis-regulatory elements that control transcriptional timing and noise in response to estrogen using single-cell RNA-seq and machine learning.

Cell Genomics · Apr 24, 2024Peer-reviewedGenomics