Jeffery M. Vahrenkamp

The paper identifies genomic features affecting ERα binding and gene expression in endometrial cancer, finding cell-type-specific transcription factors and distinct predictive features compared to breast cancer.

The paper identifies estrogen-induced chromatin looping changes in endometrial cancer cells and shows their correlation with transcriptional responses, though not all loops are essential for estrogen regulation.

This study shows ETV4 is essential for estrogen signaling and growth in endometrial cancer cells by enabling ER binding and nuclear translocation.