Alexandra Richey

The paper identifies genomic features affecting ERα binding and gene expression in endometrial cancer, finding cell-type-specific transcription factors and distinct predictive features compared to breast cancer.

The paper identifies estrogen-induced chromatin looping changes in endometrial cancer cells and shows their correlation with transcriptional responses, though not all loops are essential for estrogen regulation.

This study identifies cis-regulatory elements that control transcriptional timing and noise in response to estrogen using single-cell RNA-seq and machine learning.