Francesca Polverino

Tumor-infiltrating natural killer cell profiling for therapeutic stratification in patients with resectable non-small cell lung cancer

This study identifies smoking-associated natural killer cell subsets in NSCLC that correlate with survival and response to neoadjuvant chemoimmunotherapy, suggesting their use in therapeutic stratification.

Macropinocytosis inhibition attenuates pro-fibrotic responses in lung fibroblasts and pulmonary fibrosis

This study shows that inhibiting macropinocytosis reduces fibrotic responses in lung fibroblasts and ameliorates pulmonary fibrosis in mice.

txci-ATAC-seq, a massive-scale single-cell technique to profile chromatin accessibility

The paper introduces txci-ATAC-seq, a high-throughput single-cell ATAC-seq method, and demonstrates its application across multiple tissues and genetic backgrounds.