Daniel C. Kraushaar

This study identifies Paralemmin 2 as a lipid raft-associated protein that regulates axon initial segments and paranodal junctions through cell type-specific splicing.

This study shows that combining CDK9 inhibitors with neuropsychiatric drugs reduces diffuse midline glioma growth by altering H3 dopaminylation and CaMKII signaling.

The paper shows that overlapping MHC class I/II epitopes promote cDC1-like differentiation of moDC through mTORC1 inhibition, enhancing type 1 immunity.

This study shows that inhibiting macropinocytosis reduces fibrotic responses in lung fibroblasts and ameliorates pulmonary fibrosis in mice.

This study shows maternal vitamin C deficiency in mice leads to DNA hypermethylation and congenital defects, suggesting VitC supplementation may prevent birth defects.

This study investigates the role of oligodendrocyte AnkyrinG in age-related axoglial interactions and behavioral phenotypes, finding that its loss leads to pathophysiological changes in aged mice.

This paper develops chemotherapy-specific predictors for triple-negative breast cancer using patient-derived xenografts and multi-omic data, achieving high AUROC scores for response prediction.