Author

Federica Farinelli

Lieber Institute for Brain DevelopmentORCID 0000-0002-5126-0596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Brady J. MaheriD· 3 shared Srinidhi Rao SripathyiD· 3 shared Andrew E. JaffeiD· 2 shared Debamitra DasiD· 2 shared Gina ShimiD· 2 shared Huei-Ying CheniD· 2 shared Isaac OstlundiD· 2 shared Madhavi TippaniiD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Brady J. MaherORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 12, 2025

Automated high-throughput patch clamp electrophysiology of hiPSC-derived neuronal models

Federica Farinelli, Isaac Ostlund, Srinidhi Rao Sripathy…·Brady J. Maher

This paper introduces automated high-throughput patch clamp electrophysiology methods for hiPSC-derived neurons, enabling efficient analysis of voltage-gated sodium channels and pharmacological responses.

1 citation

humanelectronic health records

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NeuroscienceBiological PsychiatryPeer-reviewedApr 1, 2024

TCF4 mutations disrupt synaptic function through dysregulation of RIMBP2 in patient-derived cortical neurons

Brittany A. Davis, Huei-Ying Chen, Zengyou Ye…·Brady J. Maher

This study shows TCF4 mutations impair synaptic function in patient-derived cortical neurons by disrupting RIMBP2 expression, leading to deficits in synaptic transmission and network excitability.

18 citations

humanscRNA-seq

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJan 11, 2022

Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance

Stephanie C. Page, Srinidhi Rao Sripathy, Federica Farinelli…·Brady J. Maher

The paper identifies electrophysiological measures in hiPSC-derived neurons linked to schizophrenia diagnosis and cognitive performance.

67 citationstop 1%

humanbulk RNA-seq

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