Heena R. Divecha

This study maps the spatiomolecular organization of the human habenula using multi-omic approaches, identifying molecular signatures and spatial domains linked to psychiatric disorders.

This study creates a spatiomolecular atlas of the human nucleus accumbens using spatial transcriptomics and single-nucleus RNA sequencing, revealing spatial gradients and conserved features across species.

The paper integrates spatial transcriptomics and single-nucleus RNA-seq data from the human dACC to define molecular profiles, spatial domains, and functional insights.

This study maps molecular and genetic signatures of schizophrenia in human prefrontal cortex across spatial scales, revealing altered BDNF-TrkB signaling and inhibitory circuit dysfunction.

The paper creates a single-cell atlas of sex-differentially expressed genes in human hypothalamus regions, revealing molecular sex differences and their links to neurodevelopmental disorders.

The paper investigates how APOE genotype affects gene expression in the human entorhinal cortex, identifying an oligodendrocyte subtype as a potential mediator of Alzheimer's disease risk.

The paper performs transcriptomic analysis of the human habenula and identifies molecular changes associated with schizophrenia risk and illness state.

The paper analyzes the transcriptomic landscape of the human locus coeruleus in relation to Alzheimer's disease risk factors and neuromelanin content using spatially-resolved transcriptomics.

The paper integrates single-nucleus and spatial transcriptomics data to map the molecular landscape of the human hippocampus, identifying cell types and spatial domains.

This study analyzes age-related changes in gene expression in the human dentate gyrus, identifying shifts in neurogenesis, maturation, and neuroinflammation across the lifespan.

The paper generates a molecular neuroanatomical map of the human prefrontal cortex using spatial transcriptomics and single nucleus RNA-sequencing, revealing novel spatial domains and cell-cell interactions linked to psychiatric disorders.

This study investigates TrkB signaling in the lateral septum using RNA-seq, identifying gene expression changes linked to psychiatric and neurodegenerative disorders.

The paper uses spatial proteogenomics to analyze gene expression changes in Alzheimer's disease brains linked to amyloid-beta and tau pathology.

The paper identifies cell type-specific activity-regulated gene expression patterns in mouse hippocampal neurons using snRNA-seq and ECS, revealing divergent transcriptomic responses and enriched biological pathways.

The paper characterizes the molecular landscape of the human locus coeruleus using spatially-resolved transcriptomics and single-nucleus RNA-sequencing, providing a publicly accessible resource.

VistoSeg processes high-resolution Visium/Visium-IF images to integrate image-derived metrics with spatial gene expression data for spatial transcriptomics analysis.