Author

Tobias Vornholt

ETH ZurichORCID 0000-0001-9700-2384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Markus JeschekiD· 2 shared Sven PankeiD· 2 shared Thomas R. WardiD· 2 shared Andreas KrauseiD· 1 shared Christian SchellhaasiD· 1 shared Fadri ChristoffeliD· 1 shared Gregor W. SchmidtiD· 1 shared Michela M. PellizzoniiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersSynthetic Biology

Markus JeschekORCID

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2 papers

Recent·Most cited

Synthetic BiologyACS Central SciencePeer-reviewedMay 22, 2024

Enhanced Sequence-Activity Mapping and Evolution of Artificial Metalloenzymes by Active Learning

Tobias Vornholt, Mojmír Mutný, Gregor W. Schmidt…·Markus Jeschek

This paper improves enzyme engineering by combining active learning and experimental screening to efficiently discover high-performing artificial metalloenzymes.

33 citationstop 4%

machine learning (classical)drug response / drug discovery

𝕏 PostBluesky

Synthetic BiologyScience AdvancesPeer-reviewedJan 22, 2021

Systematic Engineering of Artificial Metalloenzymes for New-to-Nature Reactions

Tobias Vornholt, Fadri Christoffel, Michela M. Pellizzoni…·Markus Jeschek

This paper introduces a systematic platform for engineering artificial metalloenzymes to enhance their catalytic activity for new-to-nature reactions.

96 citationstop 2%

E. coliexperimental assay

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