Cancer BiologybioRxivPreprint
SARC028 samples reveal an interplay between TGF-beta, interferon signaling and low HLA class I expression as contributors to Ewing sarcoma checkpoint blockade resistance
Jessica D. Daley, Elina Mukherjee, David Ferraro…·Kelly M. Bailey
The paper analyzes paired tumor biopsies from Ewing sarcoma patients before and after pembrolizumab therapy to identify features of resistance to checkpoint inhibition.