NeuroscienceeLifePeer-reviewed
Mechanism for differential recruitment of orbitostriatal transmission during outcomes and actions in alcohol dependence
Rafael Renteria, Christian Cazares, Emily T. Baltz…·Christina M. Gremel
This study identifies a mechanism by which alcohol dependence disrupts OFC-DS circuit activity through D1R SPN dysfunction and increased eCB signaling, impairing outcome-based decision-making.
27 citations