Christina M. Gremel

This study shows that lateral OFC subpopulations encode current and prior action information, and their disruption affects action control and contingency reversal.

The paper shows mice use subjective experience in premotor circuits to guide behavior, with M2 and DMS involved in integrating and planning actions based on experiential variables.

This study identifies a mechanism by which alcohol dependence disrupts OFC-DS circuit activity through D1R SPN dysfunction and increased eCB signaling, impairing outcome-based decision-making.

This study shows alcohol dependence enhances action-related orbitofrontal cortex activity but reduces outcome-related activity in mice during a decision-making task.