NeurosciencebioRxivPreprint
Atxn2-CAG100-knock-in affects mouse lifespan and vestibulo-cerebellar function via neural disconnection
Melanie Vanessa Halbach, Nesli-Ece Şen, Júlia Canet-Pons…·Georg W. J. Auburger
This paper describes a novel SCA2 mouse model with CAG100 expansion in Atxn2, showing reduced lifespan and vestibulo-cerebellar dysfunction due to axon-myelin disconnection.
DOI 10.1101/333443