Meng-Hsiung Hsieh

This study shows that liver cancer initiation depends on metabolic zonation but is not linked to premalignant clonal expansion.

The paper identifies somatic TYK2 mutations in TILs that enhance anti-cancer immunity and shows their therapeutic potential through mouse models.

This study investigates how CIDEB loss-of-function mutations protect against fatty liver disease by enhancing β-oxidation through ATGL and PPARα activation.

This study shows that IGFBP2-expressing midlobular hepatocytes contribute to liver homeostasis and regeneration after injury or fasting.