Ryan K. Shields

This study examines the transcriptomic changes in Pseudomonas aeruginosa isolates before and after Imi/Rel treatment, finding diverse gene expression responses across patients.

This study compares high-depth whole genome sequencing of pooled (p-seq) and individual colonies (c5-seq) from blood culture plates to understand evolutionary dynamics in MRSA bacteremia, finding that c5-seq is more practical for tracking within-host evolution.

This study tracks genomic changes in Pseudomonas aeruginosa during antimicrobial treatment using single-isolate and metagenomic sequencing, revealing resistance mutations and population diversity.

This study examines allele-specific effects of Rifampin Resistance-Determining Region (RRDR) mutations in RpoB on E. faecium physiology and antibiotic resistance, revealing varied impacts on growth, susceptibility, and hospital survival.